双特异性磷酸酶抗体16抗体
规格:1mg/1ml
英文名: DUSP16
别名: Dual specificity phosphatase 16; Dual specificity protein phosphatase 16; DUS16_HUMAN; DUSP 16; DUSP16; KIAA1700; MAP kinase phosphatase 7; MAPK phosphatase 7; MGC129701; MGC129702; Mitogen activated
分子量: 73kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human DUSP16
交叉反应:Human, Mouse, Rat, Chicken, Cow, Zebrafish, Monkey, Chimpanzee,
细胞定位:细胞核 细胞浆
双特异性磷酸酶抗体16抗体产品介绍:background: This gene encodes a mitogen-activated protein kinase phosphatase that is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. The encoded protein specifically regulates the c-Jun amino-terminal kinase 双特异性磷酸酶抗体16抗体(JNK) and extracellular signal-regulated kinase (ERK) pathways.[provided by RefSeq, May 2010] Function: Involved in the inactivation of MAP kinases. Dephosphorylates MAPK10 bound to ARRB2. Subcellular Location: Cytoplasm. Nucleus. Cytoplasmic vesicle. After dissociation upon AGTR stimulation, re-associates with ARRB2 on endocytic vesicles. Similarity: Belongs to the protein-tyrosine phosphatase family. 双特异性磷酸酶抗体16抗体Non-receptor class dual specificity subfamily. Contains 1 rhodanese domain. Contains 1 tyrosine-protein phosphatase domain. Gene ID: 80824 Database links: Entrez Gene: 80824 Human Entrez Gene: 431336 Chicken Entrez Gene: 70686 Mouse Omim: 607175 Human SwissProt: Q9BY84 Human Unigene: 536535 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
双特异性磷酸酶抗体16抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 激酶和磷酸酶
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid