DUS2L蛋白抗体
规格：1mg/1ml
英文名： DUS2L
别名： 2310016K04Rik; dihydrouridine synthase 2 like, SMM1 homolog (S. cerevisiae); DUS2; DUS2L_HUMAN; FLJ20399; SMM1; tRNA dihydrouridine synthase 2 like; Up regulated in lung cancer; URLC8.
分子量： 55kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human DUS2L
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：
DUS2L蛋白抗体产品介绍：background: This gene encodes a cytoplasmic protein that catalyzes the conversion of uridine residues to dihydrouridine in the D-loop of tRNA. The resulting modified bases confer enhanced regional flexibility to tRNA. The encoded protein may increase the rate of translation by inhibiting an interferon-induced protein kinase. This gene has been implicated in pulmonary carcinogenesis. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Nov 2012] Function: DUS2L is a dihydrouridine DUS2L蛋白抗体synthase that catalyzes the reduction of the 5,6-double bond of a uridine residue on the displacement loop of tRNA. The resultant modified base, 5,6-dihydrouridine, appears to increase the conformational flexibility and dynamic motion of tRNA. Subcellular Location:DUS2L蛋白抗体 Cytoplasmic and Endoplasmic reticulum. Note=Mainly at the endoplasmic reticulum. Similarity: Belongs to the dus family. Dus2 subfamily. Contains 1 DRBM (double-stranded RNA-binding) domain. Gene ID: 54920 Database links: Entrez Gene: 54920 Human Omim: 609707 Human SwissProt: Q9NX74 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
DUS2L蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 转运蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid