DUS1L蛋白抗体
规格：1mg/1ml
英文名： DUS1L
别名： 1110032N12Rik; dihydrouridine synthase 1 like (S. cerevisiae); DUS1; DUS1L; DUS1L_HUMAN; PP3111; PP3111 protein; RP23-99M13.5; tRNA-dihydrouridine synthase 1-like.
分子量： 53kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human DUS1L
交叉反应：Human, Mouse, Rat, Dog, Horse, Sheep,
细胞定位：
DUS1L蛋白抗体产品介绍：background: DUS1L is a 473 amino acid protein belonging to the DUS family and DUS1 subfamily that catalyzes the synthesis of dihydrouridine, a modified base located in the D-loop of many tRNAs. DUS1L binds FAD as a cofactor and is encoded by a gene located on human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. DUS1L蛋白抗体Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it isDUS1L蛋白抗体 recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Similarity: Belongs to the dus family. Dus1 subfamily. Gene ID: 64118 Database links: Entrez Gene: 64118 Human Entrez Gene: 68730 Mouse Entrez Gene: 246185 Rat SwissProt: Q6P1R4 Human SwissProt: Q8C2P3 Mouse SwissProt: Q8K582 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or DUS1L蛋白抗体diagnostic applications.
产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 细胞凋亡
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid