神经突触素12抗体
规格:1mg/1ml
英文名: Syntaxin 12
别名: MGC51957; Stx12; STX12_HUMAN; STX13; STX14; Syntaxin-12.
分子量: 31kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Syntaxin
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep,
细胞定位:细胞膜
神经突触素12抗体产品介绍:background: Syntaxins, a family of proteins involved in the fusion of synaptic vesicles with the plasma membrane, display broad tissue distribution and contain C-terminal hydrophobic domains that direct them to their respective intracellular compartments. Syntaxin 12, also known as STX12, STX13 or STX14, is a 276 amino acid single-pass membrane protein that contains one t-SNARE coiled-coil homology domain and belongs to the Syntaxin family. Syntaxin 12 regulates protein transport between late endosomes and the神经突触素12抗体 trans-Golgi network and interacts with ABC1 (ATP-binding cassette transporter A1), a protein that facilitates cellular release of choline-phospholipids and cholesterol to apoA-I (apolipoprotein A-I). Found in recycling endosomes, Syntaxin 12 colocalizes with transferrin receptor and is encoded by a gene located on human chromosome 1. Function: SNARE that acts to regulate protein transport between late endosomes神经突触素12抗体 and the trans-Golgi network. Subcellular Location: Membrane. Golgi apparatus > trans-Golgi network membrane. Similarity: Belongs to the syntaxin family. Contains 1 t-SNARE coiled-coil homology domain. Database links: Entrez Gene: 100226 Mouse Entrez Gene: 65033 Rat SwissProt: Q9ER00 Mouse Unigene: 28237 Mouse Unigene: 54570 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
神经突触素12抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:神经生物学 信号转导 转运蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid