去泛素蛋白3抗体
规格：1mg/1ml
英文名： DUB3
别名： Cytokine inducible Deubiquitinating Enzyme; Deubiquitinating enzyme 17-like protein 2; Deubiquitinating enzyme 3; Deubiquitinating protein 3; DUB-3; DUB3 protein; U17L2_HUMAN; Ubiquitin carboxyl-termi
分子量： 60kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human DUB3
交叉反应：Human,
细胞定位：细胞核
去泛素蛋白3抗体产品介绍：background: DUB3 is a member of the ubiquitin processing protease (UBP) subfamily of deubiquitinating enzymes. See USP1 (MIM 603478) for background information.[supplied by OMIM, Mar 2008] Function: Deubiquitinating enzyme that specifically removes conjugated ubiquitin from CDC25A, thereby playing a key role in cell cycle regulation. Deubiquitination of CDC25A去泛素蛋白3抗体 prevents its degradation by the proteasome during the G1/S and G2/M phases of the cell cycle and is required for cell-cycle progression. Has transforming capabilities on cell lines. May also function in cell apoptosis. Subcellular Location: Nucleus. Tissue Specificity: Broadly expressed. Similarity: Belongs to the peptidase C19 family. USP17 subfamily. Gene ID: 377630 Database links: Entrez Gene: 377630 Human 去泛素蛋白3抗体Omim: 610186 Human SwissProt: Q6R6M4 Human Unigene: 531448 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
去泛素蛋白3抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 细胞凋亡 细胞周期蛋白 表观遗传学 泛素
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid