DTX3蛋白抗体
规格：1mg/1ml
英文名： DTX3
别名： Deltex3; Dtx3; DTX3_HUMAN; Protein deltex 3; Protein deltex-3; RING finger protein 154; RNF154.
分子量： 38kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human DTX3
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞浆
DTX3蛋白抗体产品介绍：background: DTX3 functions as an E3 ubiquitin ligase (Takeyama et al., 2003 [PubMed 12670957]).[supplied by OMIM, Nov 2009] Function: Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending onDTX3蛋白抗体 the developmental and cell context (By similarity). Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity. Subunit: Homodimer. May form a heterodimers with other members of the Deltex family. DTX3蛋白抗体Interacts with NOTCH1 (By similarity). Subcellular Location: Cytoplasm. Similarity: Belongs to the Deltex family. Contains 1 RING-type zinc finger. Gene ID: 196403 Database links: Entrez Gene: 196403 Human Entrez Gene: 80904 Mouse Omim: 613142 Human SwissProt: Q8N9I9 Human SwissProt: Q80V91 Mouse Unigene: 32374 Human Unigene: 271724 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
DTX3蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 干细胞 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid