DOCK9蛋白抗体
规格：1mg/1ml
英文名： DOCK9
别名： Cdc42 guanine nucleotide exchange factor zizimin 1; Dedicator of cytokinesis protein 9; DKFZp686C11110; DKFZp686D2047; DKFZp686N04132; DOCK 9; FLJ16744; FLJ44528; DOCK9_HUMAN; FLJ45282; FLJ45601; KIAA
分子量： 236kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human DOCK9
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep,
细胞定位：
DOCK9蛋白抗体产品介绍：background: DOCK9 is a 2,069 amino acid protein that localizes to the intracytoplasmic membrane and contains one PH domain, one DHR-1 domain and one DHR-2 domain. Expressed in a variety of tissues with highest expression in placenta and heart and lower expression in lung, kidney, brain and skeletal muscle, Zizimin-1 functions as a guanine nucleotide-exchange factor (GEF) that specifically activates Cdc42 by exchanging bound GDP for free GTP. Four isoforms of Zizimin-1 exist due to alternative splicing events. The gene encoding Zizimin-1 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% DOCK9蛋白抗体of the human genome. Trisomy 13, also known as Patau syndrome, is deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections. Function: DOCK9 is a guanine nucleotide exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Its overexpression induces filopodia formation. Subunit: HomodimerDOCK9蛋白抗体 (Probable). Interacts preferentially with nucleotide-depleted CDC42. Subcellular Location: Intracytoplasmic membrane Similarity: Belongs to the DOCK family. Contains 1 DHR-1 domain. Contains 1 DHR-2 domain. Contains 1 PH domain. Gene ID: 23348 Database links: Entrez Gene: 23348 Human Omim: 607325 Human SwissProt: Q9BZ29 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
DOCK9蛋白抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 G蛋白信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid