多药耐药相关蛋白5抗体
规格：1mg/1ml
英文名： MRP5
别名： Multidrug Resistanec-Associated Protein 5; ABC 33; ABC33; ABCC 5; ABCC5; ATP binding cassette sub family C (CFTR/MRP) member 5; ATP binding cassette sub family C member 5; Canalicular multispecific or
分子量： 160kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MRP5
交叉反应：Human, Mouse, Rat,
细胞定位：
多药耐药相关蛋白5抗体产品介绍：background: MRP5 (190-200 kDa) is closely related to MRP4, both lacking the first five membrane spanning regions. MRP5 is a GS-X multi specific organic anion pump (nucleotide analogs). MRP5 may transport DNP-GS and may be inhibited by certain inhibitors of organic anion transport (sulfinpyrazone). MRP5 may also transport organic anions with the anionic moiety of多药耐药相关蛋白5抗体 phosphate/phosphonate group, a function which provides the ability to resist against anti cancer drugs 6-MP and thioguanine as well as the anti-HIV drug PMEA. Function: Acts as a multispecific organic anion pump which can transport nucleotide analogs. Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: All isoforms are equally expressed in retina. Similarity: Belongs to the ABC多药耐药相关蛋白5抗体 transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily. Contains 2 ABC transmembrane type-1 domains. Contains 2 ABC transporter domains. Gene ID: 10057 Database links: Entrez Gene: 10057 Human Omim: 605251 Human SwissProt: O15440 Human Unigene: 368563 Human Unigene: 728765 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
多药耐药相关蛋白5抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 细胞凋亡
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid