Neuromedin-C抗体
规格：1mg/1ml
英文名： Neuromedin-C
别名： Gastrin releasing peptides; BN; Bombesin; GRP 10; GRP; GRP10; Neuromedin C; NeuromedinC; Pre progastrin releasing peptide; preproGRP; proGRP; GRP_HUMAN. Gastrin releasing peptide precursor.
分子量： 1kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Neuromed
交叉反应：Human, Mouse, Rat, Horse,
细胞定位：分泌型蛋白
Neuromedin-C抗体产品介绍：background: This gene encodes a member of the bombesin-like family of gastrin-releasing peptides. Its preproprotein, following cleavage of a signal peptide, is further processed to produce either the 27 aa gastrin-releasing peptide or the 10 aa neuromedin C. These smaller peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. These peptides are also likely to play a role in human cancers Neuromedin-C抗体of the lung, colon, stomach, pancreas, breast, and prostate. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]. Function: GRP stimulates gastrin release as well as other gastrointestinal hormones. Operates as a negative feedback regulating fear and established a causal relationship between GRP-receptor gene expression, long-term potentiation, and amygdala-dependent memory for fear. Subcellular Location: Secreted. Tissue Specificity: Highly expressed both in the lateral nucleus Neuromedin-C抗体of the amygdala, and in regions sending synaptic projections to the lateral nucleus. Similarity: ngs to the bombesin/neuromedin-B/ranatensin family. Gene ID: 2922 Database links: Entrez Gene: 2922 Human Entrez Gene: 225642 Mouse Entrez Gene: 171101 Rat Omim: 137260 Human SwissProt: P07492 Human SwissProt: Q8R1I2 Mouse SwissProt: P63153 Pig SwissProt: P24393 Rat Unigene: 153444 Human Unigene: 20298 Mouse Unigene: 10930 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Neuromedin-C抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 神经生物学 信号转导 生长因子和** 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid