DMRTC1蛋白抗体
规格：1mg/1ml
英文名： DMRTC1
别名： DMRT like family C1; Dmrtc1; DMRTC_HUMAN; DMRTC1B; Doublesex and mab 3 related transcription factor C1; Doublesex mab 3.
分子量： 20kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human DMRTC1
交叉反应：Human,
细胞定位：细胞核
DMRTC1蛋白抗体产品介绍：background: DMRTC1 is a 182 amino acid nuclear protein that exists as three alternatively spliced isoforms and belongs to the DMRT family. Involved in sexual development, DMRTC1 is expressed in Sertoli cells in male testis but, unlike other DMRT family members, it does not contain a DM DNA-binding domain. The gene encoding DMRTC1 maps to the human X chromosome, which consists of about 153 million base pairs and nearly 1,000 genes. The combination of an X and Y chromosome lead to normal male development wDMRTC1蛋白抗体hile two copies of X lead to normal female development. There are a number of conditions related to an unsual number and combination of sex chromosomes being inherited, including Klinefelter's syndrome, Turner's syndrome, and Triple X syndrome. Function: The vertebrate DMRT gene family encodes putative transcription factors related to the sexual regulators Doublesex (Drosophila) and MAB-3 (Worm). DMRTC1蛋白抗体Subcellular Location: Nuclear Tissue Specificity: Predominantly expressed in kidney, pancreas, ovary and testis. Detected in brain and in many other tissues. Similarity: Belongs to the DMRT family. Gene ID: 63947 Database links: Entrez Gene: 63947 Human Entrez Gene: 728656 Human SwissProt: Q5HYR2 Human Unigene: 558685 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
DMRTC1蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid