ATP依赖RNA解旋酶DDX6抗体
规格:1mg/1ml
英文名: DDX6
别名: ATP dependent RNA helicase DDX6; ATP dependent RNA helicase p54; DDX6; DEAD (Asp Glu Ala Asp) box polypeptide 6; DEAD box 6; DEAD box protein 6; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 6 (RNA hel
分子量: 54kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human DDX6
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit,
细胞定位:细胞浆
ATP依赖RNA解旋酶DDX6抗体产品介绍:background: This gene encodes a member of the DEAD box protein family. The protein is an RNA helicase found in P-bodies and stress granules, and functions in translation suppression and mRNA degradation. It is required for microRNA-induced gene silencing. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Mar 2012] Function: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They areATP依赖RNA解旋酶DDX6抗体 implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis and cellular growth and division. In the process of mRNA degradation, ATP依赖RNA解旋酶DDX6抗体DDX6 may play a role in mRNA decapping. It forms a complex with DCP1A, DCP2, EDC3 and EDC4/HEDLS. Subcellular Location: Cytoplasm; P-body. Note: Processing bodies (PB). Gene ID: 1656 Database links: Entrez Gene: 1656 Human Entrez Gene: 13209 Mouse Entrez Gene: 500988 Rat Omim: 600326 Human SwissProt: P26196 Human SwissProt: P54823 Mouse Unigene: 408461 Human Unigene: 267061 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
ATP依赖RNA解旋酶DDX6抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞凋亡 转录调节因子 细胞分化 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid