ATP依赖解旋酶DDX17抗体
规格：1mg/1ml
英文名： DDX17
别名： Ddx17; DDX17_HUMAN; DEAD (Asp Glu Ala Asp) box polypeptide 17; DEAD box protein 17; DEAD box protein p72; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 17; P72; Probable ATP-dependent RNA helicase DDX1
分子量： 60kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human DDX17
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep,
细胞定位：细胞核
ATP依赖解旋酶DDX17抗体产品介绍：background: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and splicesosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an ATPase activated by a variety of RNA species, but not by dsDNA. This protein, and that encoded by DDX5 gene, are more closely ATP依赖解旋酶DDX17抗体related to each other than to any other member of the DEAD box family. This gene can encode multiple isoforms due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) start codon. [provided by RefSeq, Apr 2011] Function: RNA-dependent ATPase activity. Subcellular Location: Nucleus. Tissue Specificity: Ubiquitous. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily. Contains 1 helicase ATP依赖解旋酶DDX17抗体ATP-binding domain. Contains 1 helicase C-terminal domain. Gene ID: 10521 Database links: Entrez Gene: 10521 Human Entrez Gene: 514323 Cow Entrez Gene: 67040 Mouse Entrez Gene: 315133 Rat Omim: 608469 Human SwissProt: Q92841 Human SwissProt: Q501J6 Mouse Unigene: 528305 Human Unigene: 725500 Human Unigene: 727678 Human Unigene: 29644 Mouse Unigene: 105298 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
ATP依赖解旋酶DDX17抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid