细胞色素P450 26B抗体
规格：1mg/1ml
英文名： Cytochrome P450 26B
别名： CP26; CYP26A2; CYP26B1; Cytochrome P450 26A2; Cytochrome P450 26B1; Cytochrome P450 family 26 subfamily B polypeptide 1; Cytochrome P450 retinoic acid-inactivating 2; Cytochrome P450 retinoid metaboli
分子量： 57kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Cytochro
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞膜
细胞色素P450 26B抗体产品介绍：background: This gene encodes a member of the cytochrome P450 superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein is localized to the endoplasmic reticulum, and functions as a critical regulator of all-trans retinoic acid levels by the specific inactivation of all-trans retinoic acid to hydroxylated forms. Mutations in this gene are associated with radiohumeral fusions and other skeletal and craniofacial anomalies, and increased levels of the encoded protein are associated with atherosclerotic lesions. Alternative splicing results in multiple细胞色素P450 26B抗体 transcript variants. [provided by RefSeq, Apr 2013] Function: Cytochrome P450 26B is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and the synthesis of cholesterol, steroids and other lipids. It is involved in the specific inactivation of all-trans-retinoic acid (RA) and is responsible for generation of several hydroxylated forms of RA, including 4-OH-RA, 4-oxo-RA, and 18-OH-RA. Subcellular Location: Endoplasmic reticulum membrane; microsome membrane Tissue Specificity: Highly expressed in brain, particularly in the cerebellum and pons. DISEASE: Radiohumeral fusions with other skeletal and craniofacial anomalies (RHFCA) [MIM:614416]: A disease characterized by craniofacial malformations, occipital encephalocele, radiohumeral fusions,细胞色素P450 26B抗体 oligodactyly, advanced osseous maturation, and calvarial mineralization defects. Note=The disease is caused by mutations affecting the gene represented in this entry. Similarity: Belongs to the cytochrome P450 family. Gene ID: 56603 Database links: Entrez Gene: 56603 Human Omim: 605207 Human SwissProt: Q9NR63 Human Unigene: 91546 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
细胞色素P450 26B抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 心血管 细胞生物
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid