细胞色素P450 2C18抗体
规格:1mg/1ml
英文名: CYP2C18
别名: (S) mephenytoin hydroxylase associated cytochrome P450; CPCI; CYP2C 18; CYP2C; CYP2C17; CP2CI_HUMAN; CYPIIC18; Cytochrome P450 2C18; Cytochrome P450 6B/29C; Cytochrome P450 family 2 subfamily C polype
分子量: 56kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human CYP2C18
交叉反应:Human, Mouse, Rat, Pig, Rabbit, Sheep,
细胞定位:
细胞色素P450 2C18抗体产品介绍:background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum but its specific substrate has not yet been determined. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. An additional gene, CYP2C17, was once thought to exist; however, 细胞色素P450 2C18抗体CYP2C17 is now considered an artefact based on a chimera of CYP2C18 and CYP2C19. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Function: CYP2C18 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug 细胞色素P450 2C18抗体metabolism and synthesis of cholesterol, steroids and other lipids. CYP2C18 oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Subcellular Location: Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. Gene ID: 1562 Database links: Entrez Gene: 1562 Human Omim: 601131 Human SwissProt: P33260 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
细胞色素P450 2C18抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 新陈代谢
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid