细胞色素B5还原酶样蛋白抗体
规格：1mg/1ml
英文名： CYB5RL
别名： 2810410C14Rik; Cyb5rl; Cytochrome b5 reductase-like; EC 1.6.2.2; FLJ00377; mFLJ00377; NADH-cytochrome b5 reductase-like; NB5R5_HUMAN; RP23-97J2.4.
分子量： 36kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CYB5RL
交叉反应：Human, Rat,
细胞定位：
细胞色素B5还原酶样蛋白抗体产品介绍：background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on 细胞色素B5还原酶样蛋白抗体chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple细胞色素B5还原酶样蛋白抗体 myeloma. The CYB5RL gene product has been provisionally designated CYB5RL pending further characterization. Function: NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction. Similarity: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. Contains 1 FAD-binding FR-type domain. Gene ID: 606495 Database links: Entrez Gene: 606495 Human Entrez Gene: 230582 Mouse SwissProt: Q6IPT4 Human SwissProt: B1AS42 Mouse Unigene: 591426 Human Unigene: 44608 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
细胞色素B5还原酶样蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid