CTP合成酶2抗体
规格:1mg/1ml
英文名: CTPS2
别名: CTP synthase 2; CTP synthase II; CTP synthetase 2; CTPS2; CYTIDINE 5 PRIME TRIPHOSPHATE SYNTHETASE 2; FLJ43358; MGC32997; PYRG2_HUMAN; UTP--ammonia ligase 2.
分子量: 66kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human CTPS2
交叉反应:Human, Mouse, Rat, Cow, Horse, Rabbit, Sheep,
细胞定位:
CTP合成酶2抗体产品介绍:background: The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective CTP合成酶2抗体chemotherapy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] Function: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides. Similarity: Belongs to the CTP synthase family. Contains 1 glutamine amidotransferase type-1 domain. Gene ID: 56474 Database links: Entrez Gene: 56474 Human Entrez Gene: 767849 Cow Entrez Gene: 55936 Mouse Entrez Gene: 619580 Rat Omim: 300380 Human SwissProtCTP合成酶2抗体: Q5F3Z1 Chicken SwissProt: Q1RMS2 Cow SwissProt: Q9NRF8 Human SwissProt: P70303 Mouse SwissProt: Q5U2N0 Rat Unigene: 227049 Human Unigene: 2065 Mouse Unigene: 13683 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
CTP合成酶2抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 信号转导 新陈代谢 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid