肿瘤/睾丸抗原45A4抗体
规格:1mg/1ml
英文名: CT45A4
别名: Cancer/testis antigen 45-4/6; Cancer/testis antigen 45A4/45A6; Cancer/testis antigen family 45 member A4/A6; CT45 4; CT45-4; CT45.4; CT454_HUMAN; CT45A6.
分子量: 21kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human CT45A4
交叉反应:Human,
细胞定位:细胞核
肿瘤/睾丸抗原45A4抗体产品介绍:background: CT45A4 is a 189 amino acid protein expressed in testis and in various cancer cell lines. The CT45 family comprises six highly similar (>98% cDNA identity) genes that are clustered in tandem within a 125-kb region on Xq26.3. It is suggested that CT45 is significantly phosphorylated and down-regulated during mitosis. Localized to the nucleus, CT45 may 肿瘤/睾丸抗原45A4抗体be involved in the malignancy of classical Hodgkin lymphoma in patients and is considered to be a potentially valuable cancer target. CT45 is encoded by a gene located on human chromosome X, which consists of about 153 million base pairs and nearly 1,000 genes. Color blindness, hemophilia and Duchenne muscular dystrophy are well known X chromosome-linked conditions which affect males more frequently,肿瘤/睾丸抗原45A4抗体 as males carry a single X chromosome. Tissue Specificity: Testis specific. Expressed in cancer cell lines. Gene ID: 441520 Database links: Entrez Gene: 441520 Human SwissProt: Q8N7B7 Human Unigene: 568346 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肿瘤/睾丸抗原45A4抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞类型标志物
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid