RNA冷休克域结合蛋白E1抗体
规格：1mg/1ml
英文名： CSDE1
别名： Cold shock domain containing E1 RNA binding; Cold shock domain containing protein E1; Cold shock domain-containing protein E1; Csde1; CSDE1_HUMAN; D1S155E; DKFZp779B0247; DKFZp779J1455; FLJ26882; N-ra
分子量： 89kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CSDE1
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse,
细胞定位：细胞浆
RNA冷休克域结合蛋白E1抗体产品介绍：background: UNR is a 798 amino acid protein that localizes to the cytoplasm and contains nine CDS (cold shock) domains. Existing as a component of the multi-protein autoregulatory ribonucleoprotein complex (ARC), UNR functions as an RNA-binding protein that is required for the initiation of rhinovirus RNA translation and is thought to be involved in translationally coupled mRNA turnover. UNR is expressed as two isoforms, designated long and short, and shares over 98% amino acid identity with its rat counterpart,RNA冷休克域结合蛋白E1抗体 suggesting a conserved role between species. The gene encoding UNR maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Function: RNA-binding protein. Required for internal initiation of translation of human rhinovirus RNA. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in RNA冷休克域结合蛋白E1抗体the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. Subcellular Location: Cytoplasm. Similarity: Contains 9 CSD (cold-shock) domains. Gene ID: 7812 Database links: Entrez Gene: 7812 Human Entrez Gene: 513993 Cow Entrez Gene: 229663 Mouse Entrez Gene: 117180 Rat Omim: 191510 Human SwissProt: O75534 Human SwissProt: Q91W50 Mouse SwissProt: P18395 Rat Unigene: 69855 Human Unigene: 277713 Mouse Unigene: 3562 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
RNA冷休克域结合蛋白E1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 转录调节因子 结合蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid