剪切及多聚腺苷酸化特异因子蛋白1抗体
规格：1mg/1ml
英文名： CPSF1
别名： Cleavage and polyadenylation specificity factor 160 kDa subunit; Cleavage and polyadenylation specificity factor subunit 1; CPSF 160 kDa subunit; CPSF160; HSU37012; P/cl.18.
分子量： 161kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CPSF1
交叉反应：Human, Mouse, Rat,
细胞定位：细胞核
剪切及多聚腺苷酸化特异因子蛋白1抗体产品介绍：background: Cleavage and polyadenylation specificity factor (CPSF) is a multisubunit complex that plays a central role in 3-prime processing of pre-mRNAs. CPSF recognizes the AAUAAA signal in the pre-mRNA and interacts with other proteins to facilitate both RNA cleavage and poly(A) synthesis. CPSF1 is the largest subunit of the CPSF complex (Murthy and Manley, 1995 [PubMed 7590244]).[supplied by OMIM, Mar 2008] Function: CPSF1 (Cleavage and polyadenylation specificity factor subunit 1) is a剪切及多聚腺苷酸化特异因子蛋白1抗体 component of the cleavage and polyadenylation specificity factor (CPSF) complex. It plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction. Subcellular Location: Nucleus,剪切及多聚腺苷酸化特异因子蛋白1抗体 nucleoplasm. Post-translational modifications: The N-terminus is blocked. Similarity: Belongs to the CPSF1 family. Gene ID: 29894 Database links: Entrez Gene: 29894 Human Entrez Gene: 94230 Mouse Entrez Gene: 366952 Rat Omim: 606027 Human SwissProt: Q10570 Human SwissProt: Q9EPU4 Mouse SwissProt: B5DEL2 Rat Unigene: 493202 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
剪切及多聚腺苷酸化特异因子蛋白1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid