肌动蛋白辅助蛋白类样蛋白抗体
规格：1mg/1ml
英文名： COTL1
别名： CLP; Coactosin like 1; Coactosin-like protein; COTL1; COTL1_HUMAN; FLJ43657; MGC19733.
分子量： 16kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human COTL1
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Rabbit,
细胞定位：细胞浆
肌动蛋白辅助蛋白类样蛋白抗体产品介绍：background: This gene encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis. Although this gene has been reported to map to chromosome 17 in the Smith-Magenis syndrome region, the best alignments肌动蛋白辅助蛋白类样蛋白抗体 for this gene are to chromosome 16. The Smith-Magenis syndrome region is the site of two related pseudogenes. [provided by RefSeq, Jul 2008] Function: Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization. Subcellular Location: Cytoplasm > cytoskeleton. Tissue Specificity: Widely expressed with highest levels in placenta, lung,肌动蛋白辅助蛋白类样蛋白抗体 kidney and peripheral blood leukocytes and lower levels in brain, liver and pancreas. Similarity: Belongs to the actin-binding proteins ADF family. Coactosin subfamily. Contains 1 ADF-H domain. Gene ID: 23406 Database links: Entrez Gene: 23406 Human Omim: 606748 Human SwissProt: Q14019 Human Unigene: 289092 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肌动蛋白辅助蛋白类样蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 结合蛋白 细胞骨架
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid