线粒体COQ3抗体
规格:1mg/1ml
英文名: COQ3
别名: 3 4 dihydroxy 5 hexaprenylbenzoate methyltransferase; bA9819.1; Coenzyme Q3 homolog methyltransferase (S. cerevisiae); Coenzyme Q3 homolog methyltransferase (yeast); Coenzyme Q3 homolog methyltransfer
分子量: 41kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human COQ3
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
细胞定位:
线粒体COQ3抗体产品介绍:background: Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes (Jonassen and Clarke, 2000 [PubMed 10777520]). This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. The S. cerevisiae COQ3 gene encodes an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 线粒体COQ3抗体3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 gene product is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.[supplied by OMIM, Mar 2008] Function: COQ3 (Coenzyme Q3 homolog, methyltransferase) is an O-methyltransferase essential in the线粒体COQ3抗体 biosynthetic pathway of coenzyme Q (ubiquinone). Subcellular Location: Mitochondrion matrix. Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family. Gene ID: 51805 Database links: Entrez Gene: 51805 Human Omim: 605196 Human SwissProt: Q9NZJ6 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
线粒体COQ3抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 细胞类型标志物 新陈代谢
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid