转录调节因子C/EBP β抗体
规格：1mg/1ml
英文名： CEBP Beta
别名： CEBP-beta; CLEBP beta; CCAAT Enhancer Binding Protein beta; AGP/EBP; C EBP beta; C/EBP related protein 2; CEBPB; CRP2; IL 6DBP; IL6DBP; Interleukin 6 dependent binding protein; LAP; Liver enriched tra
分子量： 36kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CEBP Bet
交叉反应：Human, Mouse, Rat, Chicken, Pig, Cow, Rabbit, Sheep,
细胞定位：
转录调节因子C/EBP β抗体产品介绍：background: The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition,转录调节因子C/EBP β抗体 the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. [provided by RefSeq]. Function: Involved in interleukin-6 signal transduction, including the transcriptional activation of acute-phase genes. Functions in brown adipose tissue (BAT) differentiation. Subunit: Binds DNA as a dimer and can form stable heterodimers with C/EBP alpha and gamma. Interacts with TRIM28 and PTGES2. Interacts with PRDM16. Interacts with CCDC85B. Subcellular Location: Nucleus. Post-translational modifications: Sumoylated by polymeric chains of SUMO2 or SUMO3. Similarity: Belongs to the bZIP family. C/EBP subfamily. Contains 1 bZIP domain. Gene ID: 转录调节因子C/EBP β抗体1051 Database links: Entrez Gene: 1051 Human Entrez Gene: 12608 Mouse Entrez Gene: 24253 Rat Omim: 189965 Human SwissProt: P17676 Human SwissProt: P28033 Mouse SwissProt: P21272 Rat Unigene: 517106 Human Unigene: 719041 Human Unigene: 720603 Human Unigene: 439656 Mouse Unigene: 6479 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 转录调节因子（Transcriptin Regulators）
转录调节因子C/EBP β抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 染色质和核信号 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid