胆碱转运体样蛋白4
规格：1mg/1ml
英文名： SLC44A4
别名： Solute carrier family 44, member 4; SLC44A4; CTL4; FLJ14491; NG22; CTL4_HUMAN.
分子量： 79kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SLC44A4
交叉反应：Human, Mouse, Rat, Horse,
细胞定位：细胞膜
胆碱转运体样蛋白4产品介绍：background: Choline is an essential nutrient that is required for the synthesis of both acetylcholine, a neurotransmitter found in cholinergic nerve terminals, and phosphatidylcholine, a key component of cell membranes. Choline deficiencies are associated with defects in cell growth and have been implicated in disorders such as Alzheimer’s and Parkinson’s disease. The choline transporter-like protein family (CTL) are solute carriers that transport choline, a compound which is not able to permeate cells, across the cell membrane.胆碱转运体样蛋白4 CTL4, also known as SLC44A4 (Solute carrier family 44 member 4), is a multi-pass membrane protein which can fuse with Neu1, generating a CTL4-Neu1 transcript. This fusion is implicated in sialidosis, a disease characterized by improper lysosomal storage. Subcellular Location: Membrane; Multi-pass membrane protein (By similarity). DISEASE: Note=An interstitial deletion causing the fusion of exon 10 of CTL4 with the 3'-UTR of NEU has been detected in two patients affected by sialidosis. Similarity: Belongs to the CTL (choline transporter-like) family. Database links: 胆碱转运体样蛋白4 UniProtKB/Swiss-Prot: Q53GD3.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
胆碱转运体样蛋白4产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **细胞
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid