碳水化合物磺基转移酶8抗体
规格：1mg/1ml
英文名： CHST8
别名： Carbohydrate (N acetylgalactosamine 4 0) sulfotransferase 8; Carbohydrate sulfotransferase 8; CHST 8; GalNAc 4 O sulfotransferase 1; GalNAc 4 ST1; CHST8_HUMAN; GalNAc4ST 1; GalNAc4ST; GALNAC4ST1; N ac
分子量： 49kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CHST9
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Rabbit,
细胞定位：
碳水化合物磺基转移酶8抗体产品介绍：background: The protein encoded by this gene belongs to the sulfotransferase 2 family. It is predominantly expressed in the pituitary gland, and is localized to the golgi membrane. This protein catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. It is responsible for sulfation of GalNAc on luteinizing hormone (LH), which is required for production of the sex hormones. Mice lacking this enzyme, exhibit increased levels of circulating LH, 碳水化合物磺基转移酶8抗体and precocious sexual maturation of both male and female mice. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2011] Function: CHST8, or Carbohydrate sulfotransferase 8, catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. It is required for biosynthesis of glycoprotein hormones lutropin and thyrotropin, by mediating sulfation of their carbohydrate structures. CHST8 is only active against terminal GalNAcbeta1 and碳水化合物磺基转移酶8抗体 GalNAcbeta and not toward chondroitin. Subcellular Location: Golgi apparatus membrane; Single-pass type II membrane protein. Similarity: Belongs to the sulfotransferase 2 family. Gene ID: 64377 Database links: Entrez Gene: 64377 Human Entrez Gene: 68947 Mouse Omim: 610190 Human SwissProt: Q9H2A9 Human SwissProt: Q8BQ86 Mouse SwissProt: B1WBV7 Rat Unigene: 165724 Human Unigene: 29380 Mouse Unigene: 55646 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
碳水化合物磺基转移酶8抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 生长因子和**
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid