染色质修饰蛋白CHMP7抗体
规格：1mg/1ml
英文名： CHMP7
别名： Charged multivesicular body protein 7; CHMP family member 7; Chromatin modifying protein 7; CHMP7_HUMAN.
分子量： 51kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CHMP7
交叉反应：Human, Mouse, Rat, Pig, Cow, Rabbit,
细胞定位：细胞浆
染色质修饰蛋白CHMP7抗体产品介绍：background: The charged multivesicular body proteins or chromatin modifying proteins, commonly designated CHMPs, belong to the vacuolar sorting protein family and function as chromatin-modifying proteins. CHMP1-6 are all components of ESCRT (endosomal sorting complex required for transport) I, II or III complexes. These complexes are crucial for sorting endosomal articles into multivesicular bodies (MVBs), as well as required for the formation of these bodies. CHMP7 is an ESCRT-III-related protein 染色质修饰蛋白CHMP7抗体that associates with CHMP4B. CHMP7 contains an SNF7 domain in the C-terminus and is most similar to CHMP6. CHMP7 also binds to the microtubule interacting and transport (MIT) domain of the deubiquitinating enzyme, UBPY. The overexpression of CHMP7 inhibits EGFR degradation. Function: CHMP7 plays a role in the endosomal sorting pathway and is a component of the ESCRT III complex. Subunit: Interacts染色质修饰蛋白CHMP7抗体 with CHMP4B, but not with VPS25. Subcellular Location: Cytoplasm. Note: Diffused localization, with some punctate distribution, especially in the perinuclear area Similarity: Belongs to the SNF7 family. Gene ID: 91782 Database links: Entrez Gene: 91782 Human Omim: 611130 Human SwissProt: Q8WUX9 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
染色质修饰蛋白CHMP7抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid