染色质解旋酶DNA结合蛋白Mi2β抗体
规格：1mg/1ml
英文名： CHD4
别名： ATP dependent helicase CHD4; ATP-dependent helicase CHD4; CHD 4; CHD-4; CHD4; CHD4_HUMAN; Chromodomain helicase DNA binding protein 4; Chromodomain-helicase-DNA-binding protein 4; Mi 2 autoantigen 218
分子量： 218kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CHD4
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
细胞定位：细胞核 细胞浆
染色质解旋酶DNA结合蛋白Mi2β抗体产品介绍：background: The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. [provided by RefSeq, Jul 2008] Function: Component染色质解旋酶DNA结合蛋白Mi2β抗体 of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Subcellular Location: Nucleus. Cytoplasm > cytoskeleton > centrosome. Associates with centrosomes in interphase. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Belongs to the SNF2/RAD54 helicase family. 染色质解旋酶DNA结合蛋白Mi2β抗体Contains 2 chromo domains. Contains 1 helicase ATP-binding domain. Contains 1 helicase C-terminal domain. Contains 2 PHD-type zinc fingers. Gene ID: 1108 Database links: Entrez Gene: 1108 Human Entrez Gene: 107932 Mouse Omim: 603277 Human SwissProt: Q14839 Human SwissProt: Q6PDQ2 Mouse Unigene: 162233 Human Unigene: 333388 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
染色质解旋酶DNA结合蛋白Mi2β抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid