细胞生长调节蛋白CGREF1抗体
规格：1mg/1ml
英文名： CGREF1
别名： Cell growth regulator with EF hand domain 1; Cell growth regulator with EF hand domain protein 1; Cell growth regulatory gene 11; Cell growth regulatory gene 11 protein; CGR 11; CGR11; CGRE1_HUMAN; CG
分子量： 30kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CGREF1
交叉反应：Human,
细胞定位：
细胞生长调节蛋白CGREF1抗体产品介绍：background: CGREF1 (cell growth regulator with EF-hand domain 1), also known as CGR11, is a 301 amino acid secreted protein that contains two highly conserved calcium binding EF-hand domains, which are required for mediating cell-cell adhesion. Induced by p53, CGREF1 is able to inhibit cell growth in various cell lines. CGREF1 is encoded by a gene located on human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity,细胞生长调节蛋白CGREF1抗体 is associated with mutations in the ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes. Additionally, an extremely rare recessive genetic disorder, Alstrom syndrome, is caused by mutations in the ALMS1 gene, which maps to chromosome 2. Function: Mediates cell-cell adhesion in a calcium-dependent manner (By similarity). Able to 细胞生长调节蛋白CGREF1抗体inhibit growth in several cell lines. Subunit: Secreted (By similarity). Similarity: Contains 2 EF-hand domains. Gene ID: 10669 Database links: Entrez Gene: 10669 Human Omim: 606137 Human SwissProt: Q99674 Human Unigene: 159525 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
细胞生长调节蛋白CGREF1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 细胞周期蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid