中心体蛋白72抗体
规格:1mg/1ml
英文名: CEP72
别名: Centrosomal protein 72kDa; Centrosomal protein of 72 kDa; Cep72; CEP72_HUMAN; FLJ10565; MGC5307; RGD1566336.
分子量: 72kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human CEP72
交叉反应:Human, Mouse, Rat, Cow, Horse, Goose,
细胞定位:细胞浆
中心体蛋白72抗体产品介绍:background: The product of this gene is a member of the leucine-rich-repeat (LRR) superfamily of proteins. The protein is localized to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. [provided by RefSeq, Jul 2008] Function: Involved in the recruitment of key centrosomal proteins to the centrosome. Provides centrosomal microtubule-nucleation activity on the gamma-tubulin ring complexes (gamma-TuRCs) and has critical roles in forming a focused bipolar spindle,中心体蛋白72抗体 which is needed for proper tension generation between sister chromatids. Required for localization of KIZ/PLK1S1, AKAP9 and gamma-tubulin ring complexes (gamma-TuRCs). Subcellular Location: Cytoplasm; cytoskeleton; centrosome. Localizes to the centrosome and 中心体蛋白72抗体centrosome-surrounding particles throughout the cell cycle. These particles disappear after microtubules are depolymerized using nocodazole, suggesting that CEP72-associating particles localize in a microtubule-dependent manner. Similarity: Belongs to the CEP72 family. Contains 3 LRR (leucine-rich) repeats. Contains 1 LRRCT domain. Gene ID: 55722 Database links: Entrez Gene: 55722 Human SwissProt: Q9P209 Human Unigene: 591741 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
中心体蛋白72抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid