唾液过氧化物酶LPO抗体
规格：1mg/1ml
英文名： Lactoperoxidase
别名： LPO; Salivary peroxidase; SAPX; SPO; PERL_HUMAN; Lactoperoxidase.
分子量： 69kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Lactoper
交叉反应：Human,
细胞定位：细胞浆
唾液过氧化物酶LPO抗体产品介绍：background: Lactoperoxidase is an antibacterial agent in cow milk. The heme protein lactoperoxidase (LPO), also referred to as salivary peroxidase (SPO), is an oxidoreductase secreted into milk. LPO, a 712 amino acid protein, belongs to the XPO subfamily of the peroxidase family. It is expressed in mammary and salivary glands, and in the presence of H2O2, LPO acts as a catalyst for the oxidation of many phenols and aromatic amines. It is crucial for protecting the lactating mammary gland and intestinal tract of newborn infants against microorganisms. LPO binds one calcium ion per heterodimer and one heme B (iron-protoporphyrin IX) group covalently per heterodimer. The LPO gene, which spans 28 kb, is similar in gene organization and sequence to the peroxidase genes MPO and EPX, suggesting the possibility 唾液过氧化物酶LPO抗体that these genes evolved from a common ancestral gene. The LPO and MPO genes are arranged in a tail-to-tail manner on chromosome 17q23.1. Function: Lactoperoxidase is a natural antibacterial agent in bovine milk, a medium otherwise rich in its ability to support bacterial growth. Milk lactoperoxidase levels vary among species, ranging from little or none in humans to very high concentrations in guinea pigs.唾液过氧化物酶LPO抗体 Interestingly, lactoperoxidase from milk is identical to the lacrimal and salivary forms of the enzyme. In addition, the enzyme catalyzes the hydrogen peroxide oxidation of iodine and can be employed in labelling proteins with radioiodine. Subcellular Location: Secreted - extracellular space Tissue Specificity: Mammary gland; milk and salivary gland. Found in bronchial submucosal glands. Similarity: Belongs to the peroxidase family. XPO subfamily. Gene ID: 4025 Database links: Entrez Gene: 4025 Human Omim: 150205 Human SwissProt: P22079 Human Unigene: 234742 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
唾液过氧化物酶LPO抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid