SHROOM1蛋白抗体
规格:1mg/1ml
英文名: SHROOM1
别名: Apical protein 2; APXL2; Protein Shroom1; SHRM1_HUMAN; Shroom family member 1; Shroom1.
分子量: 90kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human SHROOM1
交叉反应:Human, Mouse, Rat, Dog, Cow, Sheep,
细胞定位:细胞浆
SHROOM1蛋白抗体产品介绍:background: SHROOM1 is an 852 amino acid protein that contains one ASD1 domain and one ASD2 domain. Localized to both the cytoplasm and the cytoskeleton, SHROOM1 interacts with Actin and is thought to be involved in microtubule assembly during cell elongation, possibly playing a role in the development of the nervous system. Multiple isoforms of SHROOM1 exist due to alternative splicing events. The gene encoding SHROOM1 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome SHROOM1蛋白抗体5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndromeSHROOM1蛋白抗体. Function: May be involved in the assembly of microtubule arrays during cell elongation. Subcellular Location: Cytoplasm; cytoskeleton. Similarity: Belongs to the shroom family. Contains 1 ASD1 domain. Contains 1 ASD2 domain. Gene ID: 134549 Database links: Entrez Gene: 134549 Human Entrez Gene: 71774 Mouse Entrez Gene: 287285 Rat Omim: 611179 Human SwissProt: Q2M3G4 Human SwissProt: Q5SX79 Mouse Unigene: 519574 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
SHROOM1蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 信号转导 细胞骨架
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid