钙粘蛋白LKC抗体
规格：1mg/1ml
英文名： PCLKC
别名： FLJ20124; FLJ20383; MGC163154; PC LKC; PC-LKC; Protocadherin LKC; CDHR2_HUMAN.
分子量： 139kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PCLKC
交叉反应：Human, Mouse, Rat, Pig,
细胞定位：细胞膜
钙粘蛋白LKC抗体产品介绍：background: PCLKC (Protocadherin LKC) belongs to the protocadherin gene family, a subgroup of the cadherin superfamily. It is predominantly expressed in liver, kidney and colon tissues, and has a role in contact inhibition at the lateral surface of epithelial cells. It is a candidate tumor suppressor. Function: Role in contact inhibition at the lateral surface of epithelial cells. Subunit: Interacts with MAST2. Subcellular Location: Apical cell membrane; Single-pass type I membrane protein. Cell junction. Note=Present at the cell junctions and the 钙粘蛋白LKC抗体apical surface of cells. Colocalizes with actin at the microvilli-like structures which protrude from the apical surface. Tissue Specificity: Highly expressed in liver, kidney and colon. Moderately expressed in small intestine. Down-regulated in a number of liver and colon 钙粘蛋白LKC抗体cancers. Similarity: Contains 9 cadherin domains. Gene ID: 54825 Database links: Entrez Gene: 54825 Human SwissProt: Q9BYE9 Human Unigene: 4205 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
钙粘蛋白LKC抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导 细胞粘附分子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid