原钙粘附蛋白β10抗体
规格:1mg/1ml
英文名: PCDHB10
别名: OTTHUMP00000160026; PCDBA_HUMAN; PCDH BETA10; PCDH-beta-10; PCDHB10; PCHB10; Protocadherin beta-10; Protocadherin beta-10.
分子量: 84kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human PCDHB10
交叉反应:Human, Mouse, Rat, Rabbit,
细胞定位:细胞膜
原钙粘附蛋白β10抗体产品介绍:background: Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated a, b and g, all of which contain multiple tandemly-arranged genes. PCDHB10 (protocadherin b10), also known as PCHB10 or PCDH-b10, is an 800 amino acid protein that is one of 16 proteins in the protocadherin b cluster. Unlike the a and g gene clusters, whose genes are spliced to downstream constant-region exons during transcription, members of the b cluster (such as PCDHB10) do not use constant-region exons to produce 原钙粘附蛋白β10抗体mRNAs. As a result, each protocadherin b gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein. Localized to the cell membrane, PCDHB10 is a single-pass type I membrane protein that contains six cadherin domains. Function: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.原钙粘附蛋白β10抗体 Subcellular Location: Cell membrane. Similarity: Contains 6 cadherin domains. Gene ID: 56126 Database links: Entrez Gene: 56126 Human Omim: 606336 Human SwissProt: Q9UN67 Human Unigene: 657953 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
原钙粘附蛋白β10抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 神经生物学 信号转导 细胞粘附分子
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid