原钙粘附蛋白10抗体
规格：1mg/1ml
英文名： PCDH10
别名： DKFZp761O2023; KIAA1400; MGC133344; OL PCDH; Ortholog of OL pcdh; OTTHUMP00000220001; PCD10_HUMAN; PCDH10; PCDH19; Protocadherin 10; Protocadherin-10.
分子量： 110kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PCDH10
交叉反应：Human, Pig, Cow, Sheep,
细胞定位：细胞膜
原钙粘附蛋白10抗体产品介绍：background: Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDH10 (protocadherin 10), also known as PCDH19 or OL-PCDH, is a 1,040 amino acid single-pass type I membrane protein that contains six cadherin domains and one transmembrane domain.原钙粘附蛋白10抗体 Expressed at moderate levels in brain, ovary and testis and present at lower levels in all other tissues, PCDH10 functions as a calcium-dependent cell-adhesion protein that may function as a tumor suppressor. When underexpressed, PCDH10 is associated with the progression of various carcinomas, including gastric cancer. Function: Potential calcium-dependent cell-adhesion protein. Subcellular Location: Cell membrane. Tissue Specificity: Moderately expressed in all regions of the brain examined, as well as in testis and ovary, and low expression in all other tissues tested. Similarity原钙粘附蛋白10抗体: Contains 6 cadherin domains. Gene ID: 57575 Database links: Entrez Gene: 57575 Human Entrez Gene: 531875 Cow Entrez Gene: 18526 Mouse Omim: 608286 Human SwissProt: Q9P2E7 Human Unigene: 192859 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
原钙粘附蛋白10抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 神经生物学 信号转导 细胞粘附分子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid