脑钙粘蛋白12抗体
规格：1mg/1ml
英文名： CDH12
别名： Br cadherin; BR-cadherin; Brain cadherin; CAD12_HUMAN; cadherin 12 (N cadherin 2); Cadherin 12; Cadherin 12 precursor; Cadherin 12 type 2 (N cadherin 2); Cadherin 12 type 2; Cadherin neural type 2; Ca
分子量： 82kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CDH12
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞膜
脑钙粘蛋白12抗体产品介绍：background: The cadherins are a family of Ca++-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morpho-genesis (1-4). Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity (5,6). The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including脑钙粘蛋白12抗体 catenin b, to regulate cadherin function (7). BR-cadherin (for brain-cadherin, also designated cadherin-12 or N-cadherin 2) is expressed specifically in neurons in the central nervous system and is thought to be involved in neuronal development (8). Function: Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins 脑钙粘蛋白12抗体may thus contribute to the sorting of heterogeneous cell types. Subcellular Location: Cell membrane. Tissue Specificity: Brain. Similarity: Contains 5 cadherin domains. Gene ID: 1010 Database links: Entrez Gene: 1010 Human Omim: 600562 Human SwissProt: P55289 Human Unigene: 113684 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
脑钙粘蛋白12抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导 细胞粘附分子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid