肿瘤坏死因子受体相关蛋白6结合蛋白抗体
规格：1mg/1ml
英文名： TRAF6BP
别名： 1200003J11Rik; 1700069J21Rik; Aa1076; AA930106; CALCOCO 3; CALCOCO3; D6Ertd404e; D6Ertd772e; Human T cell leukemia virus type 1-binding protein; Liver regeneration-related protein LRRG004; MGC94031; P
分子量： 91kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TRAF6BP
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse, Sheep,
细胞定位：细胞浆 细胞膜
肿瘤坏死因子受体相关蛋白6结合蛋白抗体产品介绍：background: Inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degraded by caspase-3-like family proteins upon TNF-induced apoptosis. May also play a role in the pro-inflammatory cytokine IL-1 signaling cascade. Function: Inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degraded by 肿瘤坏死因子受体相关蛋白6结合蛋白抗体caspase-3-like family proteins upon TNF-induced apoptosis. May also play a role in the pro-inflammatory cytokine IL-1 signaling cascade. Subunit: Homooligomer. Interacts with TRAF6 in a IL-1-dependent manner. Interacts with TNFAIP3. Interacts with STARD13. Interacts with the HTLV-1 protein Tax-1. Tissue Specificity: Expressed in all tissues tested. Post-translational modifications肿瘤坏死因子受体相关蛋白6结合蛋白抗体Phosphorylated in the C-terminal region by CHUK/IKKA leading to NF-kappa-B signaling down-regulation. Database links: Entrez Gene: 8887 Human Entrez Gene: 52440 Mouse Entrez Gene: 246244 Rat Omim: 605326 Human SwissProt: Q86VP1 Human SwissProt: Q3UKC1 Mouse SwissProt: Q66HA4 Rat Unigene: 34576 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肿瘤坏死因子受体相关蛋白6结合蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 信号转导 细胞凋亡
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid