ILK结合蛋白LIMS2抗体
规格:1mg/1ml
英文名: LIMS2
别名: FLJ10044; ILK binding protein; LIM and senescent cell antigen like domains 2; LIM and senescent cell antigen-like-containing domain protein 2; LIM-like protein 2; LIMS2; LIMS2_HUMAN; Particularly inte
分子量: 39kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human LIMS2
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse,
细胞定位:细胞核
ILK结合蛋白LIMS2抗体产品介绍:background: Pinch is a focal adhesion protein that is a component of the ILK-PINCH complex. This complex is a major part of the growth factor and integrin signaling pathway. Pinch is involved in cell differentiation, proliferation and survival by acting as an effector of integrin and growth factor signaling. It is a cytoplasmic protein expressed in most tissues and consists of five LIM domains, a nuclear localization signal and a nuclear export signal. The PINCH-1/ILK complex is regulated by another member of the Pinch family, PINCH-2, which also forms a complex with ILK. Function: Pinch is a focal adhesion protein that is a component of the ILK-PINCH complex. This complex is aILK结合蛋白LIMS2抗体 major part of the growth factor and integrin signaling pathway. Pinch is involved in cell differentiation, proliferation and survival by acting as an effector of integrin and growth factor signaling. It is a cytoplasmic protein expressed in most tissues and consists of five LIM ILK结合蛋白LIMS2抗体domains, a nuclear localization signal and a nuclear export signal. The PINCH-1/ILK complex is regulated by another member of the Pinch family, PINCH-2, which also forms a complex with ILK. Subcellular Location: Nucleus. Cell junction > focal adhesion. Cell membrane. Similarity: Contains 5 LIM zinc-binding domains. Database links: Entrez Gene: 225341 Mouse SwissProt: Q91XD2 Mouse Unigene: 24551 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
ILK结合蛋白LIMS2抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 细胞分化 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid