T**细胞凋亡相关蛋白TDAG51抗体
规格：1mg/1ml
英文名： PHLDA1
别名： Apoptosis associated nuclear protein; Apoptosis-associated nuclear protein; DT1P1B11; MGC131738; PHLA1_HUMAN; PHLDA1; PHRIP; Pleckstrin homology like domain family A member 1; Pleckstrin homology-like
分子量： 44kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PHLDA1
交叉反应：Human, Mouse, Rat, Dog, Cow,
细胞定位：细胞核 细胞浆 细胞膜
T**细胞凋亡相关蛋白TDAG51抗体产品介绍：background: PHLDA1 is involved in regulation of apoptosis induced by signaling of T cell receptor in murine lympocytes. As any potent regulator with pleiotropic effects related to its overexpression, PHLDA attracts attention in both cell biology research and human tissue pathology. Function: Seems to be involved in regulation of apoptosis. May be involved in detachment-mediated programmed cell death. May mediate apoptosis during neuronal development. May be involved in regulation of anti-apoptotic effects T**细胞凋亡相关蛋白TDAG51抗体of IGF1. May be involved in translational regulation. Subunit: Interacts with RPL14, EIF3S7 and PABPC4. Subcellular Location: Cytoplasm. Cytoplasmic vesicle membrane. Nucleus, nucleolus. Note=Colocalizes with intracellular vesicles. Tissue Specificity: Widely expressed with highest levels in pancreas. Strongly expressed by benign melanocytic nevi, and progressively reduced expressed in primary and T**细胞凋亡相关蛋白TDAG51抗体metastatic melanomas (at protein level). Similarity: Contains 1 PH domain. Gene ID: 22822 Database links: Entrez Gene: 22822 Human Omim: 605335 Human SwissProt: Q8WV24 Human Unigene: 602085 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. TDAG51参与活化诱导的细胞凋亡，具有促进活化T细胞凋亡的作用,在**自稳中发挥重要作用。TDAG51基因在体内各组织中或多或少都有一定的表达，但其功能目前还不清楚，有待于进一步研究。
T**细胞凋亡相关蛋白TDAG51抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 细胞凋亡 t-**细胞
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid