神经细胞分化相关蛋白AHNAK抗体
规格：1mg/1ml
英文名： AHNAK
别名： AHNAK; AHNAK nucleoprotein (desmoyokin); AHNAKRS; AHNK_HUMAN; Desmoyokin; Fragments; MGC5395; Neuroblast differentiation associated protein AHNAK; Neuroblast differentiation-associated protein AHNAK;
分子量： 629kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human AHNAK
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Sheep,
细胞定位：细胞核
神经细胞分化相关蛋白AHNAK抗体产品介绍：background: AHNAK is a 5,890 amino acid protein encoded by the human gene AHNAK. The intronless AHNAK gene is located on human chromosome 11q12 and has three main structural regions: the 251 amino acid N-terminus, a large central region of 4390 amino acids with multiple repeated units of about 128 amino acids in length, and the 1002 amino acid C-terminus. The central region seems to have antiparallel beta-strands connected by intervening loops. Several putative regulatory elements are clustered within the C-terminal region, including nuclear export localization signals, a leucine zipper, and potential phosphorylation sites for Akt1 and PKC. AHNAK is believed to be an important signalling molecule involved in a wide range of physiological activities and may be required for neuronal cell differentiation..神经细胞分化相关蛋白AHNAK抗体 AHNAK also appears to influence b-adrenergic regulation of cardiac L-type Ca2+ channel function. Function: May be required for neuronal cell differentiation. Subunit: Interacts with DYSF; the interaction is direct and Ca(2+)-independent. Subcellular 神经细胞分化相关蛋白AHNAK抗体Location: Nucleus. Similarity: Contains 1 PDZ (DHR) domain. Gene ID: 79026 Database links: Entrez Gene: 79026 Human Entrez Gene: 66395 Mouse Entrez Gene: 191572 Rat Entrez Gene: 718802 Rhesus monkey Omim: 103390 Human SwissProt: Q09666 Human Unigene: 502756 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
神经细胞分化相关蛋白AHNAK抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 神经生物学 细胞分化
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid