BCL6B抗体
规格：1mg/1ml
英文名： BCL6B
别名： B cell CLL/lymphoma 6, member B (zinc finger protein); B-cell CLL/lymphoma 6, member B (zinc finger protein); BAZF; Bcl6 associated zinc finger protein; Bcl6-associated zinc finger protein; ZBTB28; Zi
分子量： 51kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human BCL6B
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Sheep,
细胞定位：细胞核
BCL6B抗体产品介绍：background: Bcl-6, a transcriptional repressor, binds Stat recognition-like DNA elements and influences germinal center development and cell differentiation. Additionally, Bcl-6 negatively regulates NFⅹB expression, thereby inhibiting NFⅹB-mediated cellular functions. Bcl-6b (B-cell CLL/lymphoma 6, member B), also known as ZNF62, BAZF or ZBTB28, is a 480 amino acid nuclear protein that contains one BTB (POZ) domain and five C2H2-type zinc fingers. Expressed ubiquitously with highest expression in placenta and heart, BCL6B抗体Bcl-6b associates with Bcl-6 and functions as a sequence-specific transcriptional repressor that is thought to be necessary for early B-cell development. The gene encoding Bcl-6b maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Function: BCL6B acts as a sequence-specific transcriptional repressor in association with BCL6. It may function in a narrow stageBCL6B抗体 or be related to some events in the early B-cell development. Subcellular Location: Nuclear Tissue Specificity: Ubiquitously expressed with higher expression found in heart and placenta. Similarity: Contains 1 BTB (POZ) domain. Contains 5 C2H2-type zinc fingers. Gene ID: 255788 Database links: Entrez Gene: 255877 Human Omim: 608992 Human SwissProt: Q8N143 Human Unigene: 22575 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
BCL6B抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 干细胞 转录调节因子 **细胞 b-**细胞 锌指蛋白 表观遗传学
储存条件： Store at -20 ∑C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid