锌指蛋白46抗体
规格：1mg/1ml
英文名： ZBTB25
别名： ZBT25_HUMAN; ZBTB25; Zinc finger and BTB domain-containing protein 25; Zinc finger protein 46; Zinc finger protein KUP.
分子量： 49kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ZBTB25/Z
交叉反应：Human, Mouse, Rat, Horse, Sheep,
细胞定位：细胞核
锌指蛋白46抗体产品介绍：background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins.锌指蛋白46抗体 Zinc finger and BTB domain-containing protein 25 (ZBTB25), also known as ZNF46 or KUP, is a 435 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus and expressed mainly in hematopoietic cells and testis, ZBTB25 contains a BTB domain, also known as a POZ domain, which inhibits DNA binding and mediates homotypic and heterotypic dimerization. Characteristics of the BTB domain suggest that ZBTB25 functions as a transcription regulator. Function: May be involved in transcriptional regulation. Subcellular Location: Nucleus.锌指蛋白46抗体 Tissue Specificity: Expressed mainly in hematopoietic cells and testis. Similarity: Contains 1 BTB (POZ) domain. Contains 2 C2H2-type zinc fingers. Database links: Entrez Gene: 7597 Human Omim: 194541 Human SwissProt: P24278 Human Unigene: 654571 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
锌指蛋白46抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 锌指蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid