锌指蛋白450抗体
规格：1mg/1ml
英文名： ZBT24
别名： ZBTB24; BIF1; ICF2; OTTHUMP00000016968; POZ (BTB) and AT hook containing zinc finger 2; ZBT24_HUMAN; Zbtb24; Zinc finger and BTB domain-containing protein 24; Zinc finger protein 450; ZNF45; PATZ2.
分子量： 78kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ZBT24/ZN
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Rabbit,
细胞定位：
锌指蛋白450抗体产品介绍：background: This gene encodes a protein similar to a protein in rodents which is induced by bone morphogenic protein 2 in vitro. [provided by RefSeq, Aug 2011] Function: May be involved in BMP2-induced transcription. Subcellular Location: Nucleus. Tissue Specificity: Widely expressed, with highest levels in naive B-cells. DISEASE: Immunodeficiency-centromeric instability-facial anomalies syndrome 2 (ICF2) [MIM:614069]: A rare disorder characterized by a variable immunodeficiency resulting in recurrent infections, facial anomalies,锌指蛋白450抗体 and branching of chromosomes 1, 9, and 16. Other variable symptoms include growth retardation, failure to thrive, and psychomotor retardation. Laboratory studies show limited hypomethylation of DNA in a small fraction of the genome in some,锌指蛋白450抗体 but not all, patients. Note=The disease is caused by mutations affecting the gene represented in this entry. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 1 A.T hook DNA-binding domain. Contains 1 BTB (POZ) domain. Contains 8 C2H2-type zinc fingers. Database links: Entrez Gene: 9841 Human Omim: 614064 Human SwissProt: O43167 Human Unigene: 409876 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
锌指蛋白450抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid