G蛋白偶联受体27抗体
规格：1mg/1ml
英文名： GPR27
别名： G protein coupled receptor 27; GPR 27; GPR27; GPR27_HUMAN; Probable G protein coupled receptor GPR27; Probable G-protein coupled receptor 27; SREB 1; SREB1; Super conserved receptor expressed in brain
分子量： 40kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SREB1
交叉反应：Human, Mouse, Rat, Cow,
细胞定位：细胞膜
G蛋白偶联受体27抗体产品介绍：background: G protein-coupled receptors (GPRs) are a protein family of transmembrane receptors that transmit an extracellular signal (ligand binding) into an intracellular signal (G protein activation). GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication. GPRs all have seven membrane-spanning domains and extracellular loops that can be glycosylated. These extracellular loops also contain two highly conserved cysteine residues which create disulfide bonds to stabilize the receptor structure. SREB1 (super conserved receptor expressed in brain 1), also known as GPR27 (G protein-coupled receptor 27), belongs to the SREB subfamily of GPRs that are expressed in the central nervous system. SREB1 may function as an amine-likeG蛋白偶联受体27抗体 GPR. Function: Orphan receptor. Possible candidate for amine-like G-protein coupled receptor. Subcellular Location: Cell membrane. Tissue Specificity: Highly expressed as a 3.0 kb transcript in brain, ovary, testis, heart, prostate and peripheral Leukocytes. Lower levels in pancreas and small intestine. A 2.3 kb transcript was also found in peripheral Leukocytes. In brain regions, detected as a 3.0 kb transcript in all regions G蛋白偶联受体27抗体tested. Highest levels in the caudate nucleus, putamen, hippocampus and subthalamic nucleus. Lowest level in the cerebellum. Similarity: Belongs to the G-protein coupled receptor 1 family. Gene ID: 2850 Database links: Entrez Gene: 2850 Human Entrez Gene: 14761 Mouse Entrez Gene: 65275 Rat Omim: 605187 Human SwissProt: Q9NS67 Human SwissProt: O54897 Mouse SwissProt: Q9JJH3 Rat Unigene: 591653 Human Unigene: 35009 Mouse Unigene: 54454 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
G蛋白偶联受体27抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:20-300 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导 G蛋白偶联受体 G蛋白信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid