糖基磷脂酰肌醇锚连接蛋白1抗体
规格：1mg/1ml
英文名： GPAA1
别名： Anchor attachment protein 1 (Gaa1p, yeast) homolog; GAA1; GAA1; GAA1; GAA1 protein homolog; Glycophosphatidylinositol anchor attachment 1; Glycosylphosphatidylinositol anchor attachment 1 protein; Gly
分子量： 68kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GPAA1
交叉反应：Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep,
细胞定位：细胞浆 细胞膜
糖基磷脂酰肌醇锚连接蛋白1抗体产品介绍：background: Glycosylphosphatidylinositol (GPI) acts as a membrane anchor for cell surface proteins. Glycosylphosphatidylinositol anchor attachment 1 protein (GPAA1), also designated GPI anchor attachment protein 1 or GAA1 protein homolog, is a membrane protein localized to the endoplasmic reticulum which is involved in GPI-anchor biosynthesis. GPAA1 is crucial for GPI-anchoring of precursor proteins and catalyzes the attachment of GPI to proteins containing a C-terminal GPR attachment signal.糖基磷脂酰肌醇锚连接蛋白1抗体 GAA1 contains an N-terminal signal sequence, one cAMP- and cGMP-dependent protein kinase phosphorylation site, two potential N-glycosylation sites, one leucine zipper pattern and eight putative transmembrane domains. GPAA1 is ubiquitously expressed and shows higher levels of expression in fetal tissues than in ***** tissues. Function: Essential for GPI-anchoring of precursor proteins but 糖基磷脂酰肌醇锚连接蛋白1抗体not for GPI synthesis. Acts before or during formation of the carbonyl intermediate. Subunit: Forms a complex with PIGK/GPI8, PIGT, PIGU and PIGS. Subcellular Location: Endoplasmic reticulum membrane. Tissue Specificity: Ubiquitously expressed in fetal and ***** tissues. Expressed at higher levels in fetal tissues than ***** tissues. Database links: UniProtKB/Swiss-Prot: O43292.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
糖基磷脂酰肌醇锚连接蛋白1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 细胞表面分子 细胞类型标志物
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid