高尔基体磷蛋白3抗体
规格：1mg/1ml
英文名： GOLPH3
别名： Coat protein GPP34; FLJ90675; Golgi peripheral membrane protein 1, 34 kDa; Golgi phosphoprotein 3 (coat protein); Golgi phosphoprotein 3; GOLP3_HUMAN; Golph3; GPP34; MIDAS; Mitochondrial DNA absence f
分子量： 34kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GOLPH3
交叉反应：Human, Mouse, Rat, Chicken, Dog, Cow, Horse,
细胞定位：细胞浆 细胞膜
高尔基体磷蛋白3抗体产品介绍：background: The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. GOLPH3L (golgi phosphoprotein 3-like), also known as GPP34R, is a 285 amino acid cytoplasmic protein that localizes to the Golgi apparatus. Belonging to the GOLPH3/VPS74 family, GOLPH3L may have a regulatory role in Golgi trafficking. GOLPH3L is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in 高尔基体磷蛋白3抗体a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma. Function: Involved in modulation of mTOR signaling. Involved in the regulation of mitochondrial lipids, leading to increase of mitochondrial mass. Potential oncogene. Subunit: Homodimer. Interacts with VPS35. Subcellular Location: Cell membrane. Endosome. Cytoplasm. Golgi apparatus > Golgi stack membrane. Mitochondrion intermembrane space. Tissue Specificity: Detected in muscle fibers of patients with mitochondrial diseases; not detected in normal muscle fibers高尔基体磷蛋白3抗体. Post-translational modifications: Phosphorylated. Similarity: Belongs to the GOLPH3/VPS74 family. Gene ID: 64083 Database links: Entrez Gene: 64083 Human Entrez Gene: 531359 Cow Entrez Gene: 66629 Mouse Entrez Gene: 78961 Rat Omim: 612207 Human SwissProt: Q9H4A6 Human SwissProt: Q9CRA5 Mouse SwissProt: Q9ERE4 Rat Unigene: 408909 Human Unigene: 250936 Mouse Unigene: 64519 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
高尔基体磷蛋白3抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导 细胞类型标志物 细胞膜蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid