谷胱甘肽S转移酶θ/Glutathione S Transferase theta 1抗体
规格：1mg/1ml
英文名： GSTT1
别名： EC 2.5.1.18; Glutathione S transferase 5; Glutathione S transferase theta 1; Glutathione S-transferase theta-1; Glutathione transferase T1 1; Glutathione transferase T1-1; GST 5 5; GST CL1; GST class
分子量： 27kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GSTT1/Gl
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞浆
谷胱甘肽S转移酶θ/Glutathione S Transferase theta 1抗体产品介绍：background: Glutathione S-transferase (GST) theta 1 (GSTT1) is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1 and GSTT2. The GSTT1 and GSTT2 share 55% amino acid sequence identity and both of them were claimed to have an important role in human carcinogenesis.谷胱甘肽S转移酶θ/Glutathione S Transferase theta 1抗体 The GSTT1 gene is located approximately 50kb away from the GSTT2 gene. The GSTT1 and GSTT2 genes have a similar structure, being composed of five exons with identical exon/intron boundaries. [provided by RefSeq, Jul 2008]. Function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Acts on 1,2-epoxy-3-(4-nitrophenoxy)propane, phenethylisothiocyanate 4-nitrobenzyl chloride and 4-nitrophenethyl bromide. Displays glutathione谷胱甘肽S转移酶θ/Glutathione S Transferase theta 1抗体peroxidase activity with cumene hydroperoxide. Subunit: Homodimer. Subcellular Location: Cytoplasm. Tissue Specificity: Found in erythrocyte. Expressed at low levels in liver. In lung, expressed at low levels in Clara cells and ciliated cells at the alveolar/bronchiolar junction. Absent from epithelial cells of larger bronchioles. Similarity: Belongs to the GST superfamily. Theta family. Contains 1 GST C-terminal domain. Contains 1 GST N-terminal domain. Database links: Entrez Gene: 2952 Human Omim: 600436 Human SwissProt: P30711 Human Unigene: 268573 Human Unigene: 720100 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
谷胱甘肽S转移酶θ/Glutathione S Transferase theta 1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 细胞类型标志物
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid