葡萄糖转运蛋白6抗体
规格：1mg/1ml
英文名： GLUT6/GLUT9
别名： Glucose Transporter GLUT6; A330096C23; F630103L12Rik; Glucose transporter type 6; Glucose transporter type 9; GLUT-6; GLUT-9; Glut6; Glut9; GTR6_HUMAN; HSA011372; RP23-449M10.2; SLC2A6; Solute carrier
分子量： 55kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GLUT6/Gl
交叉反应：Human, Mouse, Rat,
细胞定位：细胞膜
葡萄糖转运蛋白6抗体产品介绍：background: The oxidation of glucose functions as the dominant source of metabolic energy for mammals. The plasma membrane is impermeable to glucose, so the cellular uptake of this important nutrient is achieved by facultative hexose transproters (Gluts). Gluts are integral membrane proteins that transport glucose and related hexoses. Glucose binds to a Glut on one side of the membrane which provokes a conformational change causing it to release glucose to the other side. Members of the Glut family may 葡萄糖转运蛋白6抗体enhance the metabolic activity of tumor cells. Glut6 is part of the third out of three classes of Gluts. Glut6 is mainly expressed in the brain, spleen and peripheral leukocytes. It appears to be regulated by subcellular redistribution, because it is targeted to intracellular compartments by di-leucine motifs, recycling itself in a Dynamin-dependent manner. Function: Facilitative glucose transporter; binds cytochalasin B with low affinity. Subcellular Location: Cell membrane. The dileucine internalization motif is critical for intracellular sequestration. Tissue Specificity: Highly 葡萄糖转运蛋白6抗体expressed in brain, spleen and peripheral blood leukocytes. Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily. Database links: Entrez Gene: 11182 Human Omim: 606813 Human SwissProt: Q9UGQ3 Human Unigene: 244378 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
葡萄糖转运蛋白6抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:10-200 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 神经生物学 信号转导 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid