甘油磷酸二酯酶磷酸结构域4抗体
规格：1mg/1ml
英文名： GDPD1
别名： 2610020H15Rik; GDE4; Glycerophosphodiester phosphodiesterase 4; glycerophosphodiester phosphodiesterase domain containing 1; RP23-352L3.1; GDPD1_HUMAN.
分子量： 36kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GDPD1/GD
交叉反应：Human, Mouse, Rat, Dog, Cow, Rabbit, Sheep,
细胞定位：细胞浆
甘油磷酸二酯酶磷酸结构域4抗体产品介绍：background: GDE4 is a 314 amino acid cytoplasmic and multi-pass membrane protein that belongs to the glycerophosphoryl diester phosphodiesterase family. Expressed in small intestine, placenta, kidney, ovary, thymus, pancreas, spleen, liver and peripheral blood leukocytes, GDE4 contains one GDPD domain and exists as three alternatively spliced isoforms. GDE4 is encoded by a gene that maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. 甘油磷酸二酯酶磷酸结构域4抗体Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Function: This gene encodes a member of the glycerophosphodiester phosphodiesterase family of enzymes that catalyze the hydrolysis of deacylated glycerophospholipids to glycerol phosphate and alcohol. Alternative splicing results in multiple transcript variants. Subcellular Location: Cytoplasm. Membrane; Multi-pass membrane protein (Potential). Tissue Specificity: Detected in placenta, liver, kidney, pancreas, spleen, thymus, ovary, small intestine and peripheral blood 甘油磷酸二酯酶磷酸结构域4抗体leukocytes. Similarity: Belongs to the glycerophosphoryl diester phosphodiesterase family. Contains 1 GDPD domain. Database links: Entrez Gene: 284161 Human Entrez Gene: 66569 Mouse Entrez Gene: 303407 Rat SwissProt: Q8N9F7 Human SwissProt: Q9CRY7 Mouse SwissProt: Q0VGK4 Rat Unigene: 631744 Human Unigene: 281887 Mouse Unigene: 138410 Ra Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
甘油磷酸二酯酶磷酸结构域4抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid