γ-微管蛋白GCP4抗体
规格：1mg/1ml
英文名： GCP4
别名： 76P; FLJ14797; Gamma tubulin complex component 4; Gamma tubulin ring complex protein (76p gene); Gamma tubulin ring complex protein; GCP 4; GCP4; h76p; hGCP4; Hgrip76; TUBGCP 4; TUBGCP4; Tubulin gamma
分子量： 76kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GCP4
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse,
细胞定位：细胞浆
γ-微管蛋白GCP4抗体产品介绍：background: The gamma-Tubulin complex is composed of gamma Tubulin and the gamma-Tubulin complex-associated proteins GCP2, GCP3, GCP4, GCP5 and GCP6, all of which are essential components of microtubule organizing centers. gamma-Tubulin complex components are localized to both the centrosome, where they are involved in microtubule nucleation, and to the cytoplasm, where they exist as soluble complexes that can be recruited to the centrosome as needed. Although the GCP proteins are related, they γ-微管蛋白GCP4抗体have distinct roles which contribute to the proper function of the gamma-Tubulin complex. GCP4 (gamma-tubulin complex component 4), also known as TUBGCP4, is a ubiquitously expressed 667 amino acid member of the gamma-Tubulin complex that localizes to the metaphase spindle during mitosis. In response to proteosome inhibition, GCP4 exhibits increased accumulation at the pericentiolar material where it participates in microtubule organization and nucleation. Function: GCP4 is a component of the gamma-tubulin complex which is necessary for microtubule nucleationγ-微管蛋白GCP4抗体 at the centrosome. GCP4 shows sequence identity with the C-terminal regions of human centrosomal proteins 103p (TUBGCP2) and 104p (TUBGCP3). Subunit: Gamma-tubulin complex is composed of gamma-tubulin, TUBGCP2, TUBGCP3, TUBGCP4, TUBGCP5 and TUBGCP6. Interacts with NINL. Subcellular Location: Centrosome. Tissue Specificity: Ubiquitously expressed. Similarity: Belongs to the TUBGCP family. Database links: UniProtKB/Swiss-Prot: Q9UGJ1.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
γ-微管蛋白GCP4抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 细胞骨架 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid