β1-6 N-乙酰氨基葡萄糖转移酶7抗体
规格：1mg/1ml
英文名： GCNT7
别名： 3-galactosyl-O-glycosyl-glycoprotein beta-1; 6-N-acetylglucosaminyltransferase 7; Beta-1; Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7; C20orf105; GCNT; GCNT7
分子量： 49kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GCNT7
交叉反应：Human, Mouse, Rat, Horse,
细胞定位：细胞浆 细胞膜
β1-6 N-乙酰氨基葡萄糖转移酶7抗体产品介绍：background: Belonging to the glycosyltransferase 14 family, GCNT7, also known as Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7, is a 430 amino acid glycosyltransferase that is localized to the Golgi apparatus. Other members of this family include GCNT1, GCNT2, GCNT3, GCNT4 and GCNT6. GCNT1 has been shown to play an important regulatory role in the biosynthesis of mucin-type O-glycans, which serve as ligands in cell adhesion. Specifically, GCNT1β1-6 N-乙酰氨基葡萄糖转移酶7抗体 expression in leukocytes regulates the synthesis of core 2 O-glycans that carry sialyl-Lewis x (sLex) oligosaccharides, which confer high affinity binding to Selectin proteins. Since downregulation of Selectin ligand expression has been shown to inhibit tissue infiltration, glycosyltransferase 14 family members represent potential drug targets for the treatment of inflammatory disorders and other pathologiesβ1-6 N-乙酰氨基葡萄糖转移酶7抗体 involving Selectin proteins. Function: Glycosyltransferase. Subcellular Location: Golgi apparatus membrane. Similarity: Belongs to the glycosyltransferase 14 family. Database links: UniProtKB/Swiss-Prot: Q6ZNI0.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
β1-6 N-乙酰氨基葡萄糖转移酶7抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid