半乳糖激酶2抗体
规格：1mg/1ml
英文名： GALK2
别名： GaINAc Kinase; Galactokinase 2; Galactokinase-2; Galactokinase2; GALK2; GK2; MGC1745; N-acetylgalactosamine kinase; GALK2_HUMAN.
分子量： 50kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GALK2/Ga
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,
细胞定位：细胞浆
半乳糖激酶2抗体产品介绍：background: GALK2 is important in the first step of the galactose metabolism pathway. GALK1, which belongs to the GHMP kinase family of proteins, is a crucial enzyme for galactose metabolism, specifically converting ?d-galactose to galactose 1-phosphate. Defects in the gene encoding GALK1 can cause galactosemia II, an autosomal recessive disorder characterized by congenital cataracts during infancy, often within the first two weeks of life. In the ***** population, galactosemia II can cause presenile cataracts that are secondary to半乳糖激酶2抗体 accumulation of galactitol in the lens of the eye. A second gene, GALK2, encodes an enzyme with greater activity against GalNAc than galactose. GALK2 has been implicated in the salvage pathway for the reutilization of free GalNAc derived from the degradation of complex carbohydrates. Function: Acts on GalNAc. Also acts as a galactokinase when galactose is present at high concentrations. May be involved in a salvage pathway for the reutilization of free GalNAc derived from the degradation of complex carbohydrates. Belongs to the GHMP kinase family. GalK 半乳糖激酶2抗体subfamily. Subunit: Monomer. Subcellular Location: Cytoplasmic Similarity: Belongs to the GHMP kinase family. GalK subfamily. Database links: Entrez Gene: 2585 Human Entrez Gene: 69976 Mouse Omim: 137028 Human SwissProt: Q01415 Human SwissProt: Q68FH4 Mouse Unigene: 122006 Human Unigene: 738080 Human Unigene: 738534 Human Unigene: 20216 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
半乳糖激酶2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 新陈代谢
储存条件： Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid